A new study has found that among adults with eczema, proactive and long-term treatment with tacrolimus ointment applied twice a week kept the skin condition stable and reduced flare ups.
30 May, 2008 – 12:55
Conventional treatment of eczema typically involves applying anti-inflammatory medication to the infected areas of skin.
The study, published in the June edition of Allergy Magazine and carried out by Dr. Andreas Wollenberg, from Ludwig-Maximilian Universitat in Munich, Germany, and members of the European Tacrolimus Ointment Study Group, conducted a clinical trial in which 247 adult patients with eczema initially applied tacrolimus ointment twice daily for up to six -weeks to visible lesions.
Patients who responded well were then randomly assigned to apply tacrolimus or placebo ointment twice-weekly for twelve months. If flare ups occurred, they were treated with daily tacrolimus until the flare-up subsided.
The average time to a first flare up was much longer for the proactively treated patients (142 days) than for the reactively treated patients (15 days). The proactive group also had a lower percentage of days in which their condition flared up and more of them had no flare ups compared to the control group.